electrochemical determination of calcium dobesilate on graphene glassy carbon modified electrode
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abstract
graphene modified glassy carbon electrodes have been developed for the determination of calcium dobesilate in pharmaceutical formulations. the prepared graphene and cnts were used as a conductive substrate for electrochemical study of calcium dobesilate. the direct electrochemistry of calcium dobesilate showed a reversible cyclic voltammogram with a formal potential of 133 mv (vs. ag/agcl) for graphene modified electrodes in 0.1 m phosphate buffer. the linear concentration range of the sensor is 30-120 ngr for graphene modified electrode, respectively. the lifetime of biosensor is more than 2 weeks. the proposed modified electrode provides a new promising and alternative way to detect calcium dobesilate.
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Journal title:
applied biotechnology reportsجلد ۳، شماره ۱، صفحات ۳۷۳-۰
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